Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.36 |
| ▸ | GLI2 | P10070 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000460 | 0.95 | EPHX1 (0.37) | SOAT1GRM5EPHX1 | |
| SCHEMBL9000613 | 0.94 | LMNA (0.36) | SOAT1MEN1CYP2D6KMT2AGLI1 | |
| SCHEMBL9000588 | 0.93 | EPHX1 (0.38) | SOAT1GRM5EPHX1 | |
| SCHEMBL9000651 | 0.90 | SOAT1 (0.41) | SOAT1EPHX1 | |
| SCHEMBL9000579 | 0.88 | KMT2A (0.35) | SOAT1MEN1KMT2AEPHX1 | |
| SCHEMBL9000608 | 0.87 | FNTA (0.37) | SOAT1KMT2AGRM5EPHX1 | |
| SCHEMBL9000692 | 0.86 | SOAT1 (0.46) | SOAT1 | |
| SCHEMBL9000825 | 0.86 | GLI1 (0.39) | SOAT1PTGS1MEN1CYP2D6KMT2A | |
| SCHEMBL9000398 | 0.86 | EPHX1 (0.47) | SOAT1MEN1KMT2AEPHX1 | |
| SCHEMBL9000575 | 0.84 | SOAT1 (0.39) | SOAT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |