Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20789003 | 0.81 | MAPT (0.51) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6574930 | 0.80 | ALDH1A1 (0.56) | LOXL2ALDH1A1CA1CA2CA9 | |
| SCHEMBL9211381 | 0.80 | LOXL2 (0.52) | LOXL2ALDH1A1CA1CA2CA9 | |
| SCHEMBL394201 | 0.80 | LOXL2 (0.52) | LOXL2ALDH1A1CA1CA2CA9 | |
| SCHEMBL23202850 | 0.80 | CA1 (0.56) | LOXL2ALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL10563561 | 0.79 | LOXL2 (0.50) | LOXL2ALDH1A1CA1CA2CA9 | |
| SCHEMBL5186052 | 0.77 | HSD11B1 (0.49) | LOXL2ALDH1A1CA1CA2CA9 | |
| SCHEMBL3154297 | 0.77 | ALDH1A1 (0.52) | LOXL2ALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6572148 | 0.76 | HSD11B1 (0.48) | LOXL2ALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL3928206 | 0.75 | ALDH1A1 (0.50) | LOXL2ALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189871-B2 | Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2019-01-29 | — | — | US | disclosed |
| EP-3319941-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx, LLC (US) | 2018-05-16 | — | — | EP | disclosed |
| EP-3166923-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | Mallinckrodt LLC (US) | 2017-05-17 | — | — | EP | disclosed |
| US-20170044198-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-02-16 | — | — | US | disclosed |
| WO-2017011231-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | MALLINCKRODT LLC (US) | 2017-01-19 | — | — | WO | disclosed |
| US-9446393-B2 | Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2016-09-20 | — | — | US | disclosed |
| WO-2016007823-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | MALLINCKRODT LLC (US) | 2016-01-14 | — | — | WO | disclosed |
| US-20150165429-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-18 | — | — | US | disclosed |
| WO-2014018978-A2 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2014-01-30 | — | — | WO | disclosed |
| EP-0487019-B1 | Use of a nonlinear optical compound | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0384364-B1 | A composition of nonlinear optical materials and a method for preparing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5154858-A | Mixture of 2-(p-chlorophenyl)imidazoline and a compound having an electron donative and an electron attractive group | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0487019-A2 | Use of a nonlinear optical compound | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0384364-A2 | A composition of nonlinear optical materials and a method for preparing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189871-B2 | Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions | SOD1, YWHAZ, L1CAM | LOXL2 392/4885ALDH1A1 1064/4885CA1 161/4885 |
| US-20170044198-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | SOD1, C9, PYM1 | LOXL2 355/4885ALDH1A1 1211/4885CA1 150/4885 |
| US-20150165429-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | SOD1, YWHAZ, L1CAM | LOXL2 421/4885ALDH1A1 1084/4885CA1 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.