Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443676 | 0.83 | MAPT (0.34) | THRBTDP1GAAMAPTCRHBP | |
| SCHEMBL6865135 | 0.83 | F13A1 (0.38) | TDP1GAAMAPTHDAC3HDAC1 | |
| SCHEMBL10629210 | 0.83 | THRB (0.33) | THRBTDP1GAAMAPT | |
| SCHEMBL9003752 | 0.81 | ALDH1A1 (0.41) | THRBTDP1MAPTCRHBPCRHR2 | |
| SCHEMBL9683488 | 0.69 | GRIN2B (0.40) | THRBTDP1CRHBPCRHR2 | |
| SCHEMBL900832 | 0.67 | MEN1 (0.37) | THRBTDP1MAPTCRHBPCRHR2 | |
| SCHEMBL809393 | 0.66 | CRHBP (0.50) | CRHBPCRHR2 | |
| SCHEMBL9683566 | 0.66 | NPSR1 (0.33) | THRBTDP1CRHBPCRHR2 | |
| SCHEMBL9683216 | 0.64 | TSHR (0.35) | GAAMAPTCRHBPCRHR2MAPK1 | |
| SCHEMBL2810790 | 0.63 | GRM4 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491201-A | HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5338828-A | Mesogenic cyclic imino ether-containing compositions and polymerization products thereof | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5281675-A | Liquid crystal polymers | THE DOW CHEMICAL COMPANY (US) | 1994-01-25 | — | — | US | disclosed |