Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004140 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2CDK4TRPM8NPC1 | |
| SCHEMBL9004091 | 0.73 | LMNA (0.45) | LMNASMN1; SMN2CDK4TRPM8NPC1 | |
| SCHEMBL9004155 | 0.71 | LMNA (0.51) | TAS1R3TAS1R1LMNASMN1; SMN2GSK3B | |
| SCHEMBL9004128 | 0.70 | KCNH2 (0.37) | TDP1LMNA | |
| SCHEMBL9004070 | 0.67 | HSF1 (0.39) | LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9004068 | 0.66 | MAPT (0.38) | LMNASMN1; SMN2TRPM8NPC1RAB9A | |
| SCHEMBL7450494 | 0.65 | HIF1A (0.53) | SMN1; SMN2CDK4THRBATMBCHE | |
| SCHEMBL7450482 | 0.65 | HIF1A (0.53) | SMN1; SMN2CDK4THRBATMBCHE | |
| SCHEMBL9004076 | 0.65 | MCHR1 (0.46) | LMNASMN1; SMN2GSK3BTRPM8F3 | |
| SCHEMBL9004131 | 0.65 | LMNA (0.56) | TDP1TAS1R3TAS1R1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |