Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004119 | 0.85 | MAOB (0.39) | ALOX15GAASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9004095 | 0.76 | BCHE (0.53) | ALOX15SMN1; SMN2ALDH1A1RAB9ABCHE | |
| SCHEMBL9004068 | 0.73 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL14667485 | 0.70 | ALOX15 (0.63) | ALOX15GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8207242 | 0.70 | ALOX15 (0.63) | ALOX15GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9004183 | 0.68 | NFE2L2 (0.43) | SMN1; SMN2MAPTALDH1A1NPSR1RAB9A | |
| SCHEMBL24364714 | 0.67 | NPC1 (0.49) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL28543907 | 0.66 | ALOX15 (0.58) | ALOX15GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11636472 | 0.66 | LMNA (0.48) | GAASMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL9004071 | 0.65 | HTR2A (0.48) | SMN1; SMN2ALDH1A1BCHEACHEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |