Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004096 | 0.89 | ACHE (0.38) | BCHEACHEALDH1A1NPC1LMNA | |
| SCHEMBL9004105 | 0.88 | BCHE (0.49) | BCHEACHENPC1L3MBTL1LMNA | |
| SCHEMBL9004139 | 0.84 | BCHE (0.46) | BCHEACHEALDH1A1LMNACYP2D6 | |
| SCHEMBL9412227 | 0.76 | KCNH2 (0.43) | BCHEACHEALDH1A1NPC1LMNA | |
| SCHEMBL9004149 | 0.76 | KCNH2 (0.43) | BCHEACHEALDH1A1NPC1LMNA | |
| SCHEMBL9004071 | 0.76 | HTR2A (0.48) | BCHEACHEALDH1A1LMNACYP1A2 | |
| SCHEMBL9004150 | 0.75 | SIGMAR1 (0.43) | ALDH1A1NPC1RAB9ASIGMAR1MEN1 | |
| SCHEMBL9004173 | 0.74 | ALOX15 (0.50) | ALDH1A1NPC1L3MBTL1LMNACYP1A2 | |
| SCHEMBL9004102 | 0.74 | HTR2A (0.51) | BCHEACHEALDH1A1NPC1L3MBTL1 | |
| SCHEMBL9004142 | 0.73 | KCNH2 (0.42) | BCHEACHEALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |