Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004150 | 0.81 | SIGMAR1 (0.43) | SIGMAR1HRH3DRD3NPC1RAB9A | |
| SCHEMBL6548852 | 0.76 | HSP90AA1 (0.51) | SIGMAR1HRH3DRD3CHRM2CHRM4 | |
| SCHEMBL6548849 | 0.76 | HSP90AA1 (0.51) | SIGMAR1HRH3DRD3CHRM2CHRM4 | |
| SCHEMBL9004095 | 0.76 | BCHE (0.53) | SIGMAR1RAB9AALOX15MEN1ALDH1A1 | |
| SCHEMBL9004110 | 0.74 | HSP90AA1 (0.50) | HRH3ALDH1A1 | |
| SCHEMBL11631118 | 0.71 | NPC1 (0.43) | SIGMAR1HRH3DRD3NPC1RAB9A | |
| SCHEMBL11632653 | 0.71 | LMNA (0.45) | SIGMAR1HRH3DRD3NPC1RAB9A | |
| SCHEMBL11639215 | 0.70 | LMNA (0.44) | SIGMAR1HRH3DRD3NPC1RAB9A | |
| Fumaric Acid SCHEMBL11635101 | 0.69 | HRH3 (0.41) | HRH3DRD3NPC1RAB9APOLB | |
| SCHEMBL11152527 | 0.68 | ALDH1A1 (0.66) | SIGMAR1HRH3DRD3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |