Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004191 | 0.85 | KMT2A (0.37) | MEN1KMT2AADRB2 | |
| SCHEMBL9412212 | 0.76 | NOS3 (0.37) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL9004165 | 0.73 | NOS2 (0.44) | NOS3NOS1NOS2PYGL | |
| SCHEMBL9004140 | 0.71 | LMNA (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL9004070 | 0.70 | HSF1 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL9004128 | 0.69 | KCNH2 (0.37) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL9004137 | 0.69 | POLB (0.44) | MEN1KMT2A | |
| SCHEMBL9004091 | 0.64 | LMNA (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL9004145 | 0.62 | CYP3A4 (0.42) | HRH1MEN1KMT2AADRB2 | |
| SCHEMBL9412273 | 0.62 | HTR2A (0.43) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |