Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058552 | 0.97 | MAPK1 (0.36) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL2241309 | 0.82 | ALDH1A1 (0.35) | MAPK1TSHRALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL443422 | 0.79 | GPR3 (0.46) | ACHE | |
| SCHEMBL3947658 | 0.72 | HSD11B1 (0.36) | TSHRCYP3A4CYP2D6KMT2A | |
| SCHEMBL10493517 | 0.61 | TDP1 (0.41) | MAPK1TSHRALDH1A1ALOX15SLC6A2 | |
| SCHEMBL11357999 | 0.59 | MAPK1 (0.50) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| Biphenyl SCHEMBL27745920 | 0.59 | ALDH1A1 (0.69) | MAPK1TSHRALDH1A1TAAR1LMNA | |
| Iodide SCHEMBL29932508 | 0.59 | TDP1 (0.39) | MAPK1TSHRALDH1A1ALOX15SLC6A2 | |
| SCHEMBL3526796 | 0.57 | ESR1 (0.37) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL7889055 | 0.57 | CA4 (0.41) | MAPK1TSHRALDH1A1ALOX15SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523715-B1 | Photo-crosslinkable resin composition, hologram recording medium, and hologram recording method | CANON KK (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5422204-A | Mixture of polymer having a monomer containing electron donating group, halogen compound, onium salt and sensitizer, for sensitivity, storage stability | CANON KABUSHIKI KAISHA (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0523715-A1 | Photo-crosslinkable resin composition, hologram recording medium, and hologram recording method | CANON KABUSHIKI KAISHA (JP) | 1993-01-20 | — | — | EP | disclosed |