Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760301 | 0.97 | HTT (0.62) | HTTFOLH1MMEECE1SIRT5 | |
| SCHEMBL23451326 | 0.86 | HTT (0.72) | HTTFOLH1MMEECE1SIRT5 | |
| SCHEMBL23451325 | 0.86 | HTT (0.72) | HTTFOLH1MMEECE1SIRT5 | |
| SCHEMBL7701531 | 0.81 | CTRB1 (0.59) | MMEECE1CTSLCTSS | |
| SCHEMBL6850692 | 0.81 | CTRB1 (0.59) | MMEECE1CTSLCTSS | |
| SCHEMBL9825142 | 0.80 | CTSL (0.50) | CTSLCTSS | |
| SCHEMBL11148538 | 0.79 | MME (0.58) | MMEECE1CTSLCTSS | |
| SCHEMBL7757920 | 0.78 | MME (0.59) | MMEECE1CTSLCTSSCAPN1 | |
| SCHEMBL879577 | 0.78 | HTT (0.91) | HTTFOLH1PTGER4 | |
| SCHEMBL13870515 | 0.78 | CA2 (0.66) | CTSLCTSSSIRT2SIRT1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736037-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-$g(a)-AMINOALKANOYL-(S)-N-$g(a)-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |