Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826204 | 0.84 | CTSS (0.71) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9826149 | 0.83 | CTSL (0.68) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL9825813 | 0.83 | CTSL (0.68) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL7701531 | 0.83 | CTRB1 (0.59) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL6850692 | 0.83 | CTRB1 (0.59) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL9826794 | 0.82 | CTSL (0.72) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL11148538 | 0.81 | MME (0.58) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL7760301 | 0.81 | HTT (0.62) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL7757920 | 0.80 | MME (0.59) | CTSLCTSS | |
| SCHEMBL9006385 | 0.80 | HTT (0.57) | CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912120-A | Containing amine and amide substitution | SYNTEX (U.S.A.) INC. (US) | 1990-03-27 | — | — | US | disclosed |