Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CDH1 | P12830 | 1/20 | 0.34 |
| ▸ | TCF4 | P15884 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APC | P25054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007470 | 0.79 | GAA (0.41) | KDM4ENPC1KDM4AALDH1A1ABL1 | |
| SCHEMBL8950490 | 0.77 | ADRA1D (0.36) | CYP11B2ADRA1DADRA1A | |
| SCHEMBL9007469 | 0.76 | CYP2A6 (0.49) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL31699338 | 0.73 | CYP2A6 (0.44) | MAPTCYP11B2 | |
| SCHEMBL822672 | 0.72 | NR1H2 (0.47) | KDM4ENPC1KDM4AALDH1A1ABL1 | |
| SCHEMBL12681432 | 0.70 | GAA (0.42) | NPC1HTTRAB9AGABRG2GABRB3 | |
| SCHEMBL21233343 | 0.70 | CYP11B2 (0.51) | KDM4ENPC1ALDH1A1POLBRAB9A | |
| SCHEMBL21408737 | 0.70 | SMN1; SMN2 (0.49) | ALDH1A1KMT2ACYP11B2 | |
| SCHEMBL24185639 | 0.69 | NPC1 (0.39) | KDM4ENPC1KDM4AALDH1A1ABL1 | |
| SCHEMBL22130302 | 0.69 | ALDH1A1 (0.42) | KDM4ENPC1KDM4AALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| EP-3774779-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| CN-111836806-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| US-8188085-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100113439-A1 | Antifungal agents | MERCK & CO., INC. (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | KDM4E 1233/4885NPC1 3705/4885KDM4A 1277/4885 |
| US-20100113439-A1 | Antifungal agents | GMDS, GBA3, UGGT1 | KDM4E 3990/4885NPC1 287/4885KDM4A 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.