Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009877 | 0.86 | ALDH1A1 (0.51) | RAB9AKMT2ANPC1FAAHSMN1; SMN2 | |
| SCHEMBL5585773 | 0.79 | CTSK (0.48) | RAB9AKMT2ANPC1FAAHSMN1; SMN2 | |
| SCHEMBL29116605 | 0.77 | SMN1; SMN2 (0.52) | RAB9AKMT2ANPC1TAAR1FAAH | |
| SCHEMBL3645705 | 0.75 | ALDH1A1 (0.44) | RAB9AKMT2ANPC1FAAHTSHR | |
| SCHEMBL9009859 | 0.72 | HTT (0.37) | KMT2ASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL1757010 | 0.71 | EPHX1 (0.49) | RAB9AKMT2ANPC1FAAHSMN1; SMN2 | |
| SCHEMBL11738687 | 0.69 | SMN1; SMN2 (0.42) | RAB9AKMT2ANPC1TAAR1FAAH | |
| SCHEMBL11738682 | 0.69 | SMN1; SMN2 (0.42) | RAB9AKMT2ANPC1TAAR1FAAH | |
| SCHEMBL28920263 | 0.68 | FAAH (0.50) | RAB9AKMT2AFAAHSMN1; SMN2TSHR | |
| SCHEMBL29291801 | 0.68 | SMN1; SMN2 (0.61) | RAB9AKMT2ANPC1TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471280-B1 | Trans-2-acylaminocyclohexyloxyacyldipeptides | UNIV LJUBLJANI (YU) | 1996-11-06 | — | — | EP | disclosed |
| US-5231216-A | Trans-2-acylaminocyclohexyloxyacyldipeptides in the form of mixtures of diastereoisomers thereof and in the form of pure diasteredisomers, process for the preparation thereof and pharmaceutical compositions containing the same | UNIVERZA EDVARDA KARDELJA V LJUBLJANA (YU) | 1993-07-27 | — | — | US | disclosed |
| EP-0471280-A2 | Trans-2-acylaminocyclohexyloxyacyldipeptides | UNIVERZA EDVARDA KARDELJA V LJUBLJANI, VDO FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, N.SOL.O., LUBLJANA (YU) | 1992-02-19 | — | — | EP | disclosed |