Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009913 | 0.86 | RAB9A (0.45) | ALDH1A1EPHX1SMN1; SMN2MEN1POLB | |
| SCHEMBL5585773 | 0.77 | CTSK (0.48) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL19891236 | 0.76 | ALDH1A1 (0.66) | ALDH1A1GAAEPHX1LMNAHTT | |
| SCHEMBL19891239 | 0.75 | ALDH1A1 (0.68) | ALDH1A1GAAEPHX1LMNASMN1; SMN2 | |
| SCHEMBL3645705 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAALMNAHTTMEN1 | |
| SCHEMBL9009859 | 0.70 | HTT (0.37) | ALDH1A1HTTSMN1; SMN2MEN1POLB | |
| Acetic Acid SCHEMBL9470144 | 0.69 | GAA (0.78) | ALDH1A1GAAEPHX1LMNAHTT | |
| SCHEMBL2112321 | 0.68 | FAAH (0.52) | GAALMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL27720837 | 0.67 | GAA (0.59) | ALDH1A1GAAEPHX1LMNAHTT | |
| SCHEMBL11737337 | 0.67 | ALDH1A1 (0.47) | ALDH1A1GAAEPHX1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471280-B1 | Trans-2-acylaminocyclohexyloxyacyldipeptides | UNIV LJUBLJANI (YU) | 1996-11-06 | — | — | EP | disclosed |
| US-5231216-A | Trans-2-acylaminocyclohexyloxyacyldipeptides in the form of mixtures of diastereoisomers thereof and in the form of pure diasteredisomers, process for the preparation thereof and pharmaceutical compositions containing the same | UNIVERZA EDVARDA KARDELJA V LJUBLJANA (YU) | 1993-07-27 | — | — | US | disclosed |
| EP-0471280-A2 | Trans-2-acylaminocyclohexyloxyacyldipeptides | UNIVERZA EDVARDA KARDELJA V LJUBLJANI, VDO FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, N.SOL.O., LUBLJANA (YU) | 1992-02-19 | — | — | EP | disclosed |