Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010277 | 0.82 | CTSK (0.45) | CTSSSYKCTSKPOLBCTSL | |
| SCHEMBL9326555 | 0.78 | CTSS (0.44) | CTSSSYKCTSKPOLBALDH1A1 | |
| SCHEMBL9011862 | 0.77 | CTSS (0.46) | CTSSSYKCTSKPOLBALDH1A1 | |
| SCHEMBL9011863 | 0.77 | CTSS (0.46) | CTSSSYKCTSKPOLBALDH1A1 | |
| SCHEMBL8604140 | 0.77 | CTSK (0.46) | CTSSSYKCTSKPOLBCTSL | |
| SCHEMBL23789725 | 0.76 | ITGA4 (0.50) | CTSSCTSKPOLBITGA4ITGB7 | |
| SCHEMBL18970224 | 0.75 | ALDH1A1 (0.49) | CTSSSYKCTSKALDH1A1CTSL | |
| SCHEMBL18265983 | 0.75 | ALDH1A1 (0.51) | CTSSCTSKALDH1A1CTSLCTSB | |
| SCHEMBL27870024 | 0.74 | CTSS (0.43) | CTSSSYKCTSKPOLBALDH1A1 | |
| SCHEMBL5650826 | 0.74 | MMP1 (0.47) | CTSSCTSKPOLBITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |