SCHEMBL9010804

SCHEMBL9010804

[N-]=[N+]=C(S(=O)(=O)c1cccc(Cl)c1)S(=O)(=O)c1cccc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44
MMP2 P08253 1/20 0.42
FBP1 P09467 7/20 0.42
NFE2L2 Q16236 2/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3174904 0.84 MEN1 (0.41) PGRMEN1ALDH1A1KMT2AMMP2
SCHEMBL30137815 0.84 MEN1 (0.41) PGRMEN1ALDH1A1KMT2AMMP2
SCHEMBL3174918 0.83 MEN1 (0.40) MEN1ALDH1A1KMT2AMMP2FBP1
SCHEMBL30137798 0.83 MEN1 (0.40) MEN1ALDH1A1KMT2AMMP2FBP1
SCHEMBL28166172 0.82 FBP1 (0.39) MMP2FBP1
SCHEMBL9011464 0.79 ATM (0.42) PGRMMP2FLT1FLT4KDR
SCHEMBL2529402 0.79 KMT2A (0.46) MEN1ALDH1A1KMT2AFBP1
SCHEMBL11973784 0.79 MAPT (0.44) MEN1ALDH1A1KMT2AMMP2FLT1
SCHEMBL9011982 0.78 APEX1 (0.42) ALDH1A1MMP2NFE2L2FLT1FLT4
SCHEMBL547494 0.77 ALDH1A1 (0.48) MEN1ALDH1A1KMT2AMMP2FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417557-B1 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AG (DE) 1996-12-11 EP disclosed
EP-0444493-B1 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AG (DE) 1996-11-20 EP disclosed
US-5424166-A Negative-working radiation-sensitive mixture containing diazomethane acid generator and a radiation-sensitive recording material produced therfrom HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
US-5338641-A Positive-working radiation-sensitive mixture and copying material produced therefrom comprising an α,α-bis(sulfonyl) diazo methane as an acid forming compound HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-16 US disclosed
EP-0444493-A2 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-04 EP disclosed
EP-0417557-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed