SCHEMBL9011464

SCHEMBL9011464

[N-]=[N+]=C(S(=O)(=O)c1cccc(Br)c1)S(=O)(=O)c1cccc(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
BRD4 O60885 1/20 0.39
WDR5 P61964 1/20 0.39
HSD17B2 P37059 1/20 0.39
MMP2 P08253 2/20 0.38
KAT6A Q92794 2/20 0.38
KDR P35968 2/20 0.38
FLT1 P17948 1/20 0.38
FLT4 P35916 1/20 0.38
PGR P06401 1/20 0.37
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
MBTD1 Q05BQ5 1/20 0.36
L3MBTL3 Q96JM7 1/20 0.36
EDNRB P24530 2/20 0.35
EDNRA P25101 2/20 0.35
MAP4K4 O95819 1/20 0.35
PAK4 O96013 1/20 0.35
PIM1 P11309 1/20 0.35
LTK P29376 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010804 0.79 PGR (0.44) MMP2KDRFLT1FLT4PGR
SCHEMBL2529402 0.79 KMT2A (0.46)
SCHEMBL3256614 0.77 CA2 (0.45) MMP2EGFRERBB2
SCHEMBL65095 0.77 SMN1; SMN2 (0.46) ATMMMP2
SCHEMBL3177826 0.75 MEP1B (0.46) KAT6APGR
SCHEMBL28957019 0.75 HTR6 (0.44)
SCHEMBL3166268 0.75 KAT6A (0.41) KAT6AKDRPGRAURKB
SCHEMBL30137813 0.75 KAT6A (0.41) KAT6AKDRPGRAURKB
SCHEMBL101963 0.72 ALDH1A1 (0.52) ATMBRD4WDR5HSD17B2MMP2
SCHEMBL711206 0.72 TSHR (0.57) ATMBRD4WDR5HSD17B2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417557-B1 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AG (DE) 1996-12-11 EP disclosed
EP-0444493-B1 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AG (DE) 1996-11-20 EP disclosed
US-5424166-A Negative-working radiation-sensitive mixture containing diazomethane acid generator and a radiation-sensitive recording material produced therfrom HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
US-5338641-A Positive-working radiation-sensitive mixture and copying material produced therefrom comprising an α,α-bis(sulfonyl) diazo methane as an acid forming compound HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-16 US disclosed
EP-0444493-A2 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-04 EP disclosed
EP-0417557-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed