Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27317284 | 0.83 | GAA (0.62) | HTTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7811910 | 0.81 | L3MBTL1 (0.57) | NOS2HTTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9010998 | 0.81 | ALDH1A1 (0.53) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9011266 | 0.79 | ALDH1A1 (0.57) | HTTSMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL9011281 | 0.79 | NPC1 (0.56) | HTTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL9010993 | 0.77 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL9011197 | 0.77 | ALDH1A1 (0.65) | HTTKDM4EALDH1A1LMNA | |
| SCHEMBL7813471 | 0.76 | ALDH1A1 (0.47) | NOS2HTTGAAALDH1A1LMNA | |
| SCHEMBL3408619 | 0.76 | AKR1B1 (0.46) | GAAKDM4EALDH1A1LMNA | |
| 2-Thiophenenecarboxaldehyde SCHEMBL27296595 | 0.75 | NOS2 (0.37) | NOS2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| CN-1094039-A | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |