Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | USP2 | O75604 | 10/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346073 | 0.85 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CYP2D6CHRM2CYP1A2 | |
| SCHEMBL7814086 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2D6CHRM2CYP1A2 | |
| SCHEMBL9011241 | 0.81 | NOS2 (0.53) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9011281 | 0.80 | NPC1 (0.56) | ALDH1A1USP2HSD17B10HPGDTSHR | |
| SCHEMBL7813466 | 0.78 | CYP1A2 (0.48) | ALDH1A1CYP3A4CYP2D6CHRM2CYP1A2 | |
| SCHEMBL9011197 | 0.78 | ALDH1A1 (0.65) | ALDH1A1CYP3A4CHRM2CYP2C19CYP2C9 | |
| SCHEMBL9011030 | 0.77 | USP2 (0.71) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL9011044 | 0.77 | PKLR (0.47) | ALDH1A1CYP3A4CHRM2CYP1A2CYP2C19 | |
| SCHEMBL3408619 | 0.77 | AKR1B1 (0.46) | ALDH1A1CYP1A2CYP2C19HIF1AHSD17B10 | |
| SCHEMBL9011012 | 0.75 | RAB9A (0.62) | ALDH1A1SMN1; SMN2MAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |