Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508887 | 0.84 | ALDH1A1 (0.85) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7810116 | 0.82 | LMNA (0.63) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9011281 | 0.81 | NPC1 (0.56) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9011067 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ACHRM2 | |
| SCHEMBL9010998 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL9011061 | 0.77 | CCR5 (0.54) | ALDH1A1LMNACYP2C9CHRM2PKM | |
| SCHEMBL4401845 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9011241 | 0.77 | NOS2 (0.53) | ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL9011044 | 0.76 | PKLR (0.47) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL1380703 | 0.73 | LMNA (0.47) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| CN-1094039-A | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |