Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039326 | 0.90 | NPC1 (0.67) | FFAR1SIGMAR1LTA4HMAPTGAA | |
| SCHEMBL12040583 | 0.89 | SIGMAR1 (0.61) | FFAR1SIGMAR1LTA4HMAPTLMNA | |
| SCHEMBL16803105 | 0.87 | FFAR1 (0.63) | FFAR1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL4885846 | 0.87 | FFAR1 (0.63) | FFAR1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL839323 | 0.86 | DRD2 (0.71) | FFAR1DRD2DRD4DRD3GAA | |
| SCHEMBL27258307 | 0.85 | FFAR1 (0.61) | FFAR1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL12031489 | 0.85 | DRD2 (0.66) | FFAR1DRD2DRD4DRD3GAA | |
| SCHEMBL11289148 | 0.82 | LTA4H (0.66) | FFAR1LTA4HLMNANPC1RAB9A | |
| SCHEMBL7549790 | 0.82 | LTA4H (0.66) | FFAR1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL9523628 | 0.82 | DRD2 (0.68) | SIGMAR1DRD2DRD4DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512567-A | KAPPA-RECEPTOR AGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-04-30 | — | — | US | disclosed |