Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013449 | 0.89 | UTS2R (0.33) | PDE3BPDE3AUTS2R | |
| SCHEMBL9011980 | 0.87 | ADRA1D (0.38) | PDE3BPDE3AUTS2R | |
| SCHEMBL9011952 | 0.85 | UTS2R (0.37) | UTS2R | |
| SCHEMBL9329023 | 0.82 | VCP (0.32) | UTS2R | |
| SCHEMBL9012178 | 0.78 | ADRA1D (0.34) | UTS2R | |
| SCHEMBL9329176 | 0.77 | ADRA1D (0.40) | UTS2R | |
| SCHEMBL9327590 | 0.76 | TAAR1 (0.36) | UTS2R | |
| SCHEMBL6475931 | 0.74 | UTS2R (0.40) | UTS2R | |
| SCHEMBL9329085 | 0.73 | VCP (0.32) | — | |
| SCHEMBL9012300 | 0.72 | KDM4E (0.32) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |