Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL15141495 | 0.98 | ALDH1A1 (0.43) | ALDH1A1HPGDADAM17MMP1TSHR | |
| SCHEMBL232948 | 0.77 | ITGB3 (0.45) | ADAM17MMP1TSHRMAPTNTSR1 | |
| Alanine SCHEMBL601223 | 0.76 | ITGB3 (0.44) | ADAM17MMP1TSHRMAPTNTSR1 | |
| Alanine SCHEMBL3470608 | 0.74 | NTSR1 (0.39) | ALDH1A1HPGDTSHRHTTNTSR1 | |
| SCHEMBL7217344 | 0.74 | MAPT (0.53) | ALDH1A1ADAM17MMP1MAPTNTSR1 | |
| SCHEMBL7161574 | 0.71 | NPSR1 (0.48) | ADAM17MMP1MAPTNTSR1 | |
| Leucine SCHEMBL3814957 | 0.68 | ITGB3 (0.45) | ADAM17MMP1TSHRMAPTNTSR1 | |
| SCHEMBL901425 | 0.68 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHTT | |
| SCHEMBL22234035 | 0.67 | KEAP1 (0.71) | ALDH1A1HPGDTSHRMAPTHTT | |
| Leucine SCHEMBL1414045 | 0.67 | ITGB3 (0.47) | ADAM17MMP1TSHRMAPTNTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044832-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | FETZER OLIVER S (US) | 2012-04-05 | — | — | WO | disclosed |
| WO-2011090940-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2011-07-28 | — | — | WO | disclosed |