Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014383 | 0.85 | MTNR1A (0.40) | CTNNB1WNT3AMAP3K14 | |
| SCHEMBL9014723 | 0.81 | MAP3K14 (0.36) | MAP3K14 | |
| SCHEMBL9014396 | 0.80 | MAP3K14 (0.35) | MAP3K14 | |
| SCHEMBL9015271 | 0.80 | MAP3K14 (0.35) | MAP3K14CTSGKLK7KLK14KLK5 | |
| SCHEMBL9014726 | 0.76 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL9014349 | 0.74 | CHRNB4 (0.36) | MAP3K14 | |
| SCHEMBL9014647 | 0.74 | KCNH2 (0.68) | HTR1ADRD2KCNH2 | |
| SCHEMBL9014337 | 0.74 | MTNR1A (0.42) | MAP3K14 | |
| Hydrochloric Acid SCHEMBL29960788 | 0.74 | HTR1A (0.54) | HTR1ACTNNB1WNT3AMAP3K14HTR2A | |
| SCHEMBL9014727 | 0.73 | KCNH2 (0.38) | HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495022-A | Piperidines and piperazines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-02-27 | — | — | US | disclosed |
| EP-0634398-A1 | 4-Phenylpiperidinyl-1/-piperazinyl-1-ethylsubstituted benzofusedheterocycles as antiarrhythmic agents | MERCK PATENT GmbH (DE) | 1995-01-18 | — | — | EP | disclosed |