Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014886 | 0.86 | DRD3 (0.46) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9014896 | 0.83 | HSD11B1 (0.49) | DRD2HTR1AHTR2A | |
| SCHEMBL9014712 | 0.83 | DRD2 (0.57) | DRD2DRD4HTR1AHTR2AHTR7 | |
| SCHEMBL9014893 | 0.82 | HRH3 (0.50) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL9014651 | 0.82 | HTR1A (0.43) | DRD2HTR1AHTR2A | |
| SCHEMBL9014904 | 0.81 | HRH3 (0.49) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL9014815 | 0.80 | KCNH2 (0.55) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9014676 | 0.80 | HTR1A (0.47) | DRD3HTR1ASLC6A2SLC6A4ABCB1 | |
| SCHEMBL9014817 | 0.80 | HTR1A (0.52) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL9014858 | 0.79 | KCNH2 (0.57) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578596-A | TREATMENT OF SEROTONERGIC NEURON RELATED DISEASES, MOTION SICKNESS, ANXIXETY, DEPRESSION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0668276-A1 | 2-ALKOXY-5,6,7,8-TETRAHYDROQUINOXALINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-08-23 | — | — | EP | disclosed |