Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014892 | 0.83 | KCNH2 (0.56) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL9014823 | 0.83 | HRH3 (0.43) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL9014847 | 0.82 | HPGD (0.55) | KDM4ELMNAMAPTHPGDTSHR | |
| SCHEMBL9014715 | 0.81 | HTR1A (0.43) | HTR1A | |
| SCHEMBL9014678 | 0.79 | KCNH2 (0.40) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL9014877 | 0.78 | DRD2 (0.52) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL9014689 | 0.78 | HTR1A (0.47) | HTR1A | |
| SCHEMBL9014886 | 0.78 | DRD3 (0.46) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL9014676 | 0.78 | HTR1A (0.47) | HTR1ADRD3KCNH2 | |
| SCHEMBL9014893 | 0.78 | HRH3 (0.50) | HTR1ADRD2HTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578596-A | TREATMENT OF SEROTONERGIC NEURON RELATED DISEASES, MOTION SICKNESS, ANXIXETY, DEPRESSION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0668276-A1 | 2-ALKOXY-5,6,7,8-TETRAHYDROQUINOXALINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-08-23 | — | — | EP | disclosed |