Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754223 | 0.89 | PPM1A (0.38) | GPR3FFAR4NPC1RAB9ASCN5A | |
| SCHEMBL9015207 | 0.80 | CRHBP (0.49) | LMNACYP1A2CYP3A4GAASMN1; SMN2 | |
| SCHEMBL9015155 | 0.72 | CYP1A2 (0.35) | NPC1RAB9ACYP1A2KDM4E | |
| SCHEMBL9015179 | 0.71 | KDM4E (0.45) | NPC1RAB9ALMNACYP1A2GAA | |
| SCHEMBL12369504 | 0.70 | GPR3 (0.59) | GPR3FFAR4NPC1RAB9ASCN5A | |
| SCHEMBL874383 | 0.69 | NPC1 (0.36) | GPR3NPC1RAB9ASCN5AGMNN | |
| SCHEMBL5763105 | 0.68 | KDM4E (0.33) | NPC1RAB9AKDM4E | |
| SCHEMBL6088423 | 0.68 | ALDH1A1 (0.36) | NPC1RAB9AUSP2TP53CYP1A2 | |
| SCHEMBL9015199 | 0.68 | ALOX15 (0.35) | NPC1RAB9AALOX15MAPK1L3MBTL1 | |
| SCHEMBL6090040 | 0.68 | ACHE (0.49) | RAB9ALMNACYP1A2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054845-C | Quinoline compounds | NOVARTIS AG (CH) | 2000-07-26 | — | — | CN | disclosed |
| US-5508408-A | LEUKOTRIENE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| CN-1105991-A | Quinoline compounds | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | CN | disclosed |