Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 4/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901818 | 0.79 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL10188661 | 0.74 | DGAT1 (0.46) | CDK9CCNT1DGAT1 | |
| SCHEMBL10188922 | 0.70 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL10189110 | 0.69 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL902608 | 0.68 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL901617 | 0.67 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL901616 | 0.67 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL10189191 | 0.66 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL902393 | 0.66 | DGAT1 (0.42) | CDK9CCNT1DGAT1 | |
| SCHEMBL902786 | 0.66 | DGAT1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |