Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016476 | 0.87 | ESR2 (0.36) | AGTR1AGTR2CNR1NR3C1ABL1 | |
| SCHEMBL8873723 | 0.84 | ESR2 (0.34) | AGTR1AGTR2CNR1NR3C1ABL1 | |
| SCHEMBL8872253 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2NR3C1ABL1GABRA1 | |
| SCHEMBL9016411 | 0.82 | SLC6A9 (0.40) | CNR1NR3C1GABRA1GABRG2GABRB3 | |
| SCHEMBL9016423 | 0.80 | PPARG (0.46) | AGTR1AGTR2CNR1NR3C1GABRA1 | |
| SCHEMBL8958791 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2LMNA | |
| SCHEMBL9016493 | 0.78 | APLNR (0.42) | AGTR1AGTR2NR3C1 | |
| SCHEMBL8872592 | 0.76 | AGTR1 (0.50) | AGTR1AGTR2CNR2 | |
| SCHEMBL8872236 | 0.73 | AGTR1 (0.69) | AGTR1AGTR2CNR2 | |
| SCHEMBL9016407 | 0.73 | ALDH1A1 (0.38) | AGTR1AGTR2LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |