SCHEMBL9017293

SCHEMBL9017293

N#Cc1c(Cl)c(C(F)(F)F)n(COC(=O)CNS(=O)(=O)c2ccccc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MMP1 P03956 2/20 0.36
MMP12 P39900 2/20 0.36
GAA P10253 1/20 0.36
MEP1B Q16820 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
PKM P14618 1/20 0.35
IDH2 P48735 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP7 P09237 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
MMP14 P50281 1/20 0.35
ADAM17 P78536 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017309 0.85 KMT2A (0.49) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9017316 0.83 RXFP1 (0.37) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9017310 0.82 KMT2A (0.47) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL8994390 0.75 L3MBTL1 (0.35) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9017291 0.74 DAGLA (0.39) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL8994386 0.73 PAX8 (0.35) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9017343 0.73 KMT2A (0.44) MAPTALDH1A1MMP1GAAMEN1
SCHEMBL5815133 0.73 KDM4E (0.36) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL9036751 0.73 KDM4E (0.39) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL5812558 0.71 RXFP1 (0.36) MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594942-B1 N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-09-04 EP claimed
EP-0594942-A1 N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed
US-5286743-A N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-02-15 US claimed