Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTKDM4EGLA | |
| SCHEMBL811578 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTCYP3A4FFAR4 | |
| SCHEMBL21263 | 0.73 | ALDH1A1 (0.69) | ALDH1A1CYP3A4AHR | |
| SCHEMBL28298270 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CYP3A4AHR | |
| SCHEMBL1816933 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CYP3A4AHR | |
| SCHEMBL12501 | 0.71 | ALDH1A1 (0.73) | ALDH1A1HPGDMAPTKDM4EGLA | |
| SCHEMBL145855 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTKDM4EGLA | |
| SCHEMBL16959281 | 0.71 | LMNA (0.53) | ALDH1A1MAPTKDM4EGLAELANE | |
| SCHEMBL9017643 | 0.70 | FFAR4 (0.42) | MAPTPTPN1FFAR4TP53RAB9A | |
| SCHEMBL8999515 | 0.69 | KMT2A (0.44) | ALDH1A1MAPTELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538847-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-07-23 | — | — | US | disclosed |