Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977482 | 0.88 | ALDH1A1 (0.42) | ENPP2CALM1PTGS2PTPN1NOS2 | |
| Butane SCHEMBL16290769 | 0.83 | PTGS2 (0.42) | ENPP2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28961393 | 0.83 | CALM1 (0.51) | CALM1PTGS2PTPN1NOS2TP53 | |
| SCHEMBL5162931 | 0.77 | FFAR4 (0.37) | FFAR4MARS1CNR1ENPP2GRIN2D | |
| SCHEMBL8507775 | 0.75 | IDO1 (0.57) | IDO1CTBP2 | |
| SCHEMBL8507266 | 0.74 | IDO1 (0.52) | IDO1CALM1NPC1TP53HTT | |
| SCHEMBL6368476 | 0.74 | MARS1 (0.42) | FFAR4MARS1CNR1GRIN2DGRIN3B | |
| SCHEMBL28917699 | 0.74 | TP53 (0.38) | TP53CYP19A1 | |
| SCHEMBL1977481 | 0.73 | ALDH1A1 (0.46) | CALM1PTGS2PTPN1NOS2CYP19A1 | |
| SCHEMBL3933664 | 0.73 | MARS1 (0.41) | FFAR4MARS1CNR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538847-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-07-23 | — | — | US | disclosed |