Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018390 | 0.91 | CA1 (0.44) | ALDH1A1SMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL9018079 | 0.90 | ALDH1A1 (0.42) | POLBALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL9138028 | 0.89 | POLB (0.47) | POLBALDH1A1GAASMN1; SMN2GLA | |
| SCHEMBL9018210 | 0.89 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL9018062 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL9018028 | 0.87 | PTPN1 (0.53) | POLBALDH1A1GAASMN1; SMN2SGMS1 | |
| SCHEMBL9018384 | 0.86 | LMNA (0.43) | POLBALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL9018388 | 0.86 | LMNA (0.41) | POLBALDH1A1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL9018268 | 0.86 | RAB9A (0.46) | POLBALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL9018267 | 0.85 | HSD17B10 (0.45) | POLBALDH1A1SMN1; SMN2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |