Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018504 | 0.92 | CA12 (0.46) | P4HTMMEN1USP2KMT2AHSD17B10 | |
| SCHEMBL9018407 | 0.91 | ATM (0.41) | P4HTMATMMEN1USP2KMT2A | |
| SCHEMBL9018165 | 0.89 | PTPN1 (0.51) | P4HTMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9018503 | 0.89 | HSD17B10 (0.50) | P4HTMMEN1USP2KMT2AHSD17B10 | |
| SCHEMBL9018559 | 0.87 | MEN1 (0.53) | P4HTMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9018022 | 0.86 | ALDH1A1 (0.60) | MEN1KMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7869445 | 0.86 | PKM (0.43) | P4HTMATMMEN1USP2KMT2A | |
| SCHEMBL9018365 | 0.86 | L3MBTL1 (0.61) | P4HTMMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL9018162 | 0.85 | SMN1; SMN2 (0.54) | P4HTMMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL7874562 | 0.85 | EGFR (0.43) | P4HTMATMMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |