Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018476 | 0.91 | HTT (0.50) | ALDH1A1HSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9018095 | 0.91 | LMNA (0.47) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL9018263 | 0.91 | HTT (0.51) | ALDH1A1HSD17B10SMN1; SMN2HTTKMT2A | |
| SCHEMBL9018178 | 0.88 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9018055 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTKMT2A | |
| SCHEMBL9018331 | 0.84 | RAB9A (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL9017983 | 0.84 | CA12 (0.46) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL9018075 | 0.84 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2HTTKMT2AGAA | |
| SCHEMBL9018177 | 0.83 | RAB9A (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2HTT | |
| SCHEMBL9018252 | 0.83 | MEN1 (0.39) | ALDH1A1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |