Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018845 | 0.82 | VNN1 (0.39) | VNN1MAOBGRIN2B | |
| SCHEMBL9018853 | 0.80 | BCL2A1 (0.39) | CYP3A4 | |
| SCHEMBL9508158 | 0.77 | GRIN2B (0.47) | GRIN2B | |
| SCHEMBL9419947 | 0.76 | PAX8 (0.49) | PAX8VNN1MAOBCYP1A1CYP1B1 | |
| SCHEMBL1121810 | 0.73 | SERPINE1 (0.37) | VNN1MAOB | |
| SCHEMBL6339735 | 0.72 | PTPN1 (0.56) | VNN1CYP1A1CYP1B1SRD5A2CES2 | |
| SCHEMBL9018882 | 0.70 | L3MBTL1 (0.47) | CYP3A4CES2CES1GRIN2B | |
| SCHEMBL9018902 | 0.69 | EPHX2 (0.52) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL1567951 | 0.66 | CA2 (0.57) | MAOBSRD5A2MAPK8CES2CES1 | |
| SCHEMBL4847457 | 0.65 | PTPN1 (0.63) | MAOBSRD5A2CES2CES1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |