Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411738 | 0.72 | ALDH1A1 (0.42) | THRBALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL788147 | 0.69 | TRPV4 (0.44) | ALDH1A1MAPTTDP1L3MBTL1TRPV4 | |
| SCHEMBL31556483 | 0.69 | TRPV4 (0.44) | ALDH1A1MAPTTDP1L3MBTL1TRPV4 | |
| SCHEMBL8197493 | 0.68 | TRPV4 (0.53) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL28819768 | 0.68 | TSHR (0.50) | THRBALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL28977921 | 0.67 | TTR (0.46) | ALDH1A1TDP1CYP3A4HPGDTSHR | |
| SCHEMBL38143 | 0.67 | TTR (0.50) | ALDH1A1TDP1CA1CA2CA4 | |
| SCHEMBL28444885 | 0.65 | TTR (0.48) | ALDH1A1TDP1CA1CA2CA4 | |
| SCHEMBL7959632 | 0.65 | TRPV4 (0.38) | ALDH1A1TRPV4 | |
| SCHEMBL28457862 | 0.65 | CA2 (0.52) | THRBALDH1A1RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445926-B1 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RES CORP (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5240464-A | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0445926-A2 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |