Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432675 | 0.80 | ALDH1A1 (0.46) | KMT2AATMMAPTALDH1A1HSD17B10 | |
| SCHEMBL34465393 | 0.80 | ALDH1A1 (0.46) | KMT2AATMMAPTALDH1A1HSD17B10 | |
| SCHEMBL28927012 | 0.77 | GABRP (0.41) | KMT2AMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL8580446 | 0.76 | KDM4E (0.50) | MAPTALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL2161703 | 0.75 | PARP1 (0.36) | KMT2AMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5316536 | 0.73 | BCAT2 (0.41) | KMT2AATMMAPTALDH1A1HSD17B10 | |
| SCHEMBL11901445 | 0.73 | PLA2G2A (0.46) | KMT2AMAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL7844303 | 0.72 | MAPK8 (0.40) | ALDH1A1DGAT1LMNAPARP1 | |
| SCHEMBL1018547 | 0.71 | PARP1 (0.42) | KMT2AATMMAPTALDH1A1HSD17B10 | |
| SCHEMBL17836871 | 0.71 | ERN1 (0.47) | KMT2AATMMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |