Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021593 | 0.89 | POLB (0.38) | DYRK1ACDK9NOS2ADORA2AADORA2B | |
| SCHEMBL7112477 | 0.82 | NOS2 (0.34) | NOS2ADORA2AADORA2BADORA1GAA | |
| SCHEMBL8871239 | 0.71 | NOS3 (0.33) | DYRK1ACDK9NOS2 | |
| SCHEMBL9021891 | 0.70 | ADORA3 (0.36) | ADORA2AADORA2BADORA1GAATSHR | |
| SCHEMBL3243411 | 0.69 | ALDH1A1 (0.41) | TLR8GAATSHRALDH1A1HPGD | |
| SCHEMBL8871376 | 0.65 | NOS3 (0.30) | NOS2 | |
| SCHEMBL4138900 | 0.64 | HPGD (0.42) | ADORA2ATSHRALDH1A1HPGD | |
| SCHEMBL2336285 | 0.64 | ALDH1A1 (0.45) | ADORA2AADORA2BTSHRALDH1A1HPGD | |
| SCHEMBL4148123 | 0.63 | ADRA2A (0.42) | TLR8ADORA2BTSHRALDH1A1HPGD | |
| SCHEMBL9703916 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397511-B1 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY LTD (KR) | 1996-09-04 | — | — | EP | disclosed |
| US-5202315-A | Antiboiotic | LUCKY, LTD. (KR) | 1993-04-13 | — | — | US | disclosed |
| WO-1992008721-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | LUCKY, LTD. (KR) | 1992-05-29 | — | — | WO | disclosed |
| EP-0397511-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY, LTD. (KR) | 1990-11-14 | — | — | EP | disclosed |