Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 14/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902149 | 0.77 | DGAT1 (0.62) | DGAT1KCNH2ADORA2ASOAT1PTGDR2 | |
| SCHEMBL902748 | 0.77 | DGAT1 (0.55) | DGAT1KCNH2ADORA2ASOAT1PTGDR2 | |
| SCHEMBL902020 | 0.76 | DGAT1 (0.59) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL901002 | 0.76 | DGAT1 (0.74) | DGAT1KCNH2ADORA2ASOAT1PTGDR2 | |
| SCHEMBL901150 | 0.76 | DGAT1 (0.53) | DGAT1KCNH2ADORA2ASOAT1FASN | |
| SCHEMBL901617 | 0.75 | DGAT1 (0.50) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL902764 | 0.73 | DGAT1 (0.42) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL902559 | 0.72 | DGAT1 (0.61) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL14971589 | 0.71 | DGAT1 (0.65) | DGAT1KCNH2ADORA2ASOAT1PTGDR2 | |
| SCHEMBL902702 | 0.70 | DGAT1 (0.47) | DGAT1KCNH2ADORA2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |