SCHEMBL9022245

SCHEMBL9022245

C[CH]c1cccc(S(C)(=O)=O)c1S(C)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
BCAT2 O15382 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719846 0.80 BCAT2 (0.38) BCAT2
SCHEMBL7211351 0.71 GAA (0.46) BCAT2
SCHEMBL31672192 0.71 GAA (0.46) BCAT2
SCHEMBL5545192 0.71 DRD2 (0.33) BCAT2
SCHEMBL27960209 0.69 ALDH1A1 (0.45) BRD4CREBBP
SCHEMBL17680988 0.69 BRD4 (0.43) BRD4CREBBPBCAT2
SCHEMBL536001 0.68 LMNA (0.52) BRD4CREBBPBCAT2
SCHEMBL8106699 0.67 LOX (0.47) BCAT2
SCHEMBL5095373 0.67 TDP1 (0.39)
SCHEMBL7175797 0.67 CA2 (0.50) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711775-A1 1,2,4-triazole alkylation ROHM AND HAAS COMPANY (US) 1996-05-15 EP disclosed
US-5510493-A Process for alkylation with triazoles ROHM AND HAAS COMPANY (US) 1996-04-23 US disclosed
US-5192783-A Fungicides for plants ROHM AND HAAS COMPANY (US) 1993-03-09 US disclosed
US-4366165-A 1 and 4-Arylcyanoalkyl-1,2,4-triazoles and fungicidal use ROHM AND HAAS COMPANY (US) 1982-12-28 US disclosed