Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022603 | 0.85 | CTSS (0.42) | KIF11CYP11B2ALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL9023051 | 0.84 | PARP1 (0.42) | CYP11B2MAPTALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL9022740 | 0.84 | MAOA (0.51) | CYP11B2MAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9023138 | 0.81 | CYP11B2 (0.51) | CYP11B2MAPTALDH1A1TDP1MAOA | |
| SCHEMBL9023294 | 0.78 | MAOA (0.41) | CYP11B2MAPTALDH1A1TDP1MAOA | |
| SCHEMBL9022441 | 0.78 | MAOA (0.54) | CYP11B2MAPTALDH1A1TDP1MAOA | |
| SCHEMBL9023167 | 0.77 | PGR (0.45) | CYP11B2MAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9022513 | 0.77 | MAOA (0.40) | CYP11B2MAPTALDH1A1TDP1MAOA | |
| SCHEMBL9022520 | 0.77 | MAOA (0.40) | CYP11B2MAPTALDH1A1TDP1MAOA | |
| SCHEMBL9378933 | 0.76 | MAOA (0.39) | CYP11B2MAPTALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470665-B1 | 1-Hydroxyindole fungicides | EASTMAN KODAK CO (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0472231-B1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK CO (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5183894-A | Agricultural fungicides | EASTMAN KODAK COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5118695-A | 1-HYDROXYINDOLE FUNGICIDES | EASTMAN KODAK COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0472231-A1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0470665-A1 | 1-Hydroxyindole fungicides | EASTMAN KODAK COMPANY (US) | 1992-02-12 | — | — | EP | disclosed |