SCHEMBL9023167

SCHEMBL9023167

N#Cc1c(-c2ccc(C(=O)c3ccccc3)cc2)n(O)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.45
ALDH1A1 P00352 5/20 0.43
MAPK1 P28482 1/20 0.43
STAT3 P40763 1/20 0.43
ELANE P08246 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TSHR P16473 1/20 0.40
AGTR1 P30556 1/20 0.39
CYP11B2 P19099 1/20 0.39
ATM Q13315 1/20 0.38
SRD5A2 P31213 1/20 0.38
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
HK1 P19367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022740 0.85 MAOA (0.51) ALDH1A1MAPK1STAT3KMT2AMEN1
SCHEMBL9023051 0.80 PARP1 (0.42) ALDH1A1MAPK1STAT3KMT2AMEN1
SCHEMBL9022394 0.80 ALDH1A1 (0.47) ALDH1A1MAPK1STAT3ELANEKMT2A
SCHEMBL9023294 0.80 MAOA (0.41) ALDH1A1MAPK1STAT3KMT2AMEN1
SCHEMBL9023203 0.77 MEN1 (0.47) ALDH1A1MAPK1KMT2AMEN1LMNA
SCHEMBL9023138 0.77 CYP11B2 (0.51) ALDH1A1MAPK1STAT3KMT2AMEN1
SCHEMBL9022441 0.77 MAOA (0.54) ALDH1A1MAPK1KMT2AMEN1LMNA
SCHEMBL9022797 0.77 KIF11 (0.41) ALDH1A1MAPK1STAT3ELANEKMT2A
SCHEMBL9022520 0.76 MAOA (0.40) ALDH1A1MAPK1STAT3KMT2AMEN1
SCHEMBL9022513 0.76 MAOA (0.40) ALDH1A1MAPK1STAT3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470665-B1 1-Hydroxyindole fungicides EASTMAN KODAK CO (US) 1996-04-24 EP disclosed
US-5118695-A 1-HYDROXYINDOLE FUNGICIDES EASTMAN KODAK COMPANY (US) 1992-06-02 US disclosed
EP-0470665-A1 1-Hydroxyindole fungicides EASTMAN KODAK COMPANY (US) 1992-02-12 EP disclosed