Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774188 | 0.79 | TRPA1 (0.49) | — | |
| SCHEMBL17350953 | 0.76 | SLC18A2 (0.44) | SLC18A2 | |
| SCHEMBL4862038 | 0.75 | TAAR1 (0.40) | — | |
| SCHEMBL28308626 | 0.73 | MAOA (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11457409 | 0.71 | ARG1 (0.34) | — | |
| SCHEMBL9752704 | 0.71 | MAPT (0.42) | — | |
| SCHEMBL17785261 | 0.70 | SLC18A2 (0.34) | SLC18A2 | |
| SCHEMBL29789748 | 0.70 | NPC1 (0.39) | SLC18A2 | |
| SCHEMBL9752857 | 0.70 | LMNA (0.50) | — | |
| SCHEMBL4558511 | 0.70 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452074-B1 | Ergoline-8-carboxamides for blocking 5HT receptors | LILLY CO ELI (US) | 1996-01-24 | — | — | EP | disclosed |