Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037758 | 0.79 | KDM4E (0.42) | CYP11B2RECQLSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9023138 | 0.78 | CYP11B2 (0.51) | CYP11B2EGFRSRCSQORKDM4E | |
| SCHEMBL9022740 | 0.76 | MAOA (0.51) | CYP11B2SMN1; SMN2EGFRSRCKDM4E | |
| SCHEMBL9023051 | 0.72 | PARP1 (0.42) | CYP11B2SMN1; SMN2EGFRSRCSQOR | |
| SCHEMBL31273342 | 0.71 | SMN1; SMN2 (0.40) | CYP11B2RECQLSMN1; SMN2EGFRSRC | |
| SCHEMBL9022330 | 0.71 | MEN1 (0.43) | CYP11B2RECQLEGFRSRCKDM4E | |
| SCHEMBL9023167 | 0.70 | PGR (0.45) | CYP11B2SMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL9381891 | 0.69 | ALDH1A1 (0.38) | CYP11B2EGFRSRCKDM4EALDH1A1 | |
| SCHEMBL22562508 | 0.69 | GRM5 (0.42) | CYP11B2RECQLSMN1; SMN2SQORKDM4E | |
| SCHEMBL9023294 | 0.69 | MAOA (0.41) | CYP11B2EGFRSRCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472231-B1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK CO (US) | 1994-10-26 | — | — | EP | claimed |
| EP-0472231-A1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK COMPANY (US) | 1992-02-26 | — | — | EP | claimed |
| EP-0470665-B1 | 1-Hydroxyindole fungicides | EASTMAN KODAK CO (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0472231-B1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK CO (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5183894-A | Agricultural fungicides | EASTMAN KODAK COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5118695-A | 1-HYDROXYINDOLE FUNGICIDES | EASTMAN KODAK COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0472231-A1 | 2-Substituted-1-hydroxyindoles | EASTMAN KODAK COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0470665-A1 | 1-Hydroxyindole fungicides | EASTMAN KODAK COMPANY (US) | 1992-02-12 | — | — | EP | disclosed |