Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966618 | 0.91 | ALDH1A1 (0.47) | ALDH1A1HTTRAB9ANPC1TP53 | |
| SCHEMBL9080507 | 0.89 | AOC3 (0.45) | AOC3ALDH1A1HTTRAB9AHSP90AA1 | |
| SCHEMBL9079669 | 0.85 | CHRNB2 (0.40) | AOC3ALDH1A1HTTRAB9AHSP90AA1 | |
| SCHEMBL6974227 | 0.85 | NPC1 (0.44) | RAB9ANPC1RIPK1MEN1KMT2A | |
| SCHEMBL6969265 | 0.84 | ALDH1A1 (0.41) | AOC3ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6969688 | 0.82 | ALDH1A1 (0.46) | AOC3ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6972036 | 0.81 | ALDH1A1 (0.50) | AOC3ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6971987 | 0.79 | ALDH1A1 (0.42) | AOC3ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6970199 | 0.76 | RAB9A (0.40) | ALDH1A1HTTRAB9ANPC1TP53 | |
| SCHEMBL9080811 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |