Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970199 | 0.91 | RAB9A (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL6960285 | 0.86 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL9024045 | 0.85 | AOC3 (0.41) | HSP90AA1ALDH1A1HTTRAB9AMEN1 | |
| SCHEMBL9024167 | 0.83 | YWHAG (0.41) | ALDH1A1MEN1KMT2ASLC2A1POLB | |
| SCHEMBL9080507 | 0.81 | AOC3 (0.45) | HSP90AA1ALDH1A1HTTRAB9AMEN1 | |
| SCHEMBL6966618 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HTTRAB9ANPC1TP53 | |
| SCHEMBL7972578 | 0.76 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL6972036 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL6969265 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL9080811 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |