Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079669 | 0.91 | CHRNB2 (0.40) | RAB9AALDH1A1HTTCHRNB2CHRNB4 | |
| SCHEMBL6960285 | 0.90 | CHRNB2 (0.50) | RAB9ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6966618 | 0.84 | ALDH1A1 (0.47) | RAB9AALDH1A1HTTNPC1TP53 | |
| SCHEMBL6969265 | 0.83 | ALDH1A1 (0.41) | RAB9AALDH1A1HTTNPC1TP53 | |
| SCHEMBL6972584 | 0.81 | L3MBTL1 (0.43) | ALDH1A1PPARDPPARAPPARGPOLB | |
| SCHEMBL6972036 | 0.81 | ALDH1A1 (0.50) | RAB9AALDH1A1HTTNPC1TP53 | |
| SCHEMBL6965330 | 0.81 | ESR1 (0.42) | RAB9ANPC1TP53SMN1; SMN2HRH4 | |
| SCHEMBL6974399 | 0.81 | ESR1 (0.42) | RAB9ANPC1TP53SMN1; SMN2HRH4 | |
| SCHEMBL6968612 | 0.79 | ROCK2 (0.47) | RAB9ANPC1POLBSMN1; SMN2CNR1 | |
| SCHEMBL6970271 | 0.79 | HRH4 (0.44) | POLBHRH4HRH3LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |