Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023702 | 0.99 | HTR7 (0.57) | HTR7CHRM1DRD2CHRM2CHRM4 | |
| SCHEMBL9029235 | 0.91 | ADRB2 (0.49) | HTR7CHRM1DRD2CHRM2CHRM4 | |
| SCHEMBL5658698 | 0.84 | ALDH1A1 (0.63) | HTR7DRD2DRD3SIGMAR1MEN1 | |
| SCHEMBL9024845 | 0.83 | CHRM1 (0.48) | CHRM1DRD2CHRM2CHRM4CHRM5 | |
| SCHEMBL9024825 | 0.83 | CHRM1 (0.71) | HTR7CHRM1DRD2CHRM2CHRM4 | |
| SCHEMBL5729537 | 0.82 | HTR7 (0.63) | HTR7DRD2DRD3SIGMAR1MEN1 | |
| SCHEMBL9024063 | 0.82 | CHRM1 (0.73) | HTR7CHRM1DRD2CHRM2CHRM4 | |
| SCHEMBL9024576 | 0.81 | SIGMAR1 (0.51) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL9373505 | 0.81 | HTR1A (0.69) | HTR7DRD2DRD3ALDH1A1LMNA | |
| SCHEMBL9024164 | 0.80 | SIGMAR1 (0.50) | HTR7SIGMAR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463810-B1 | Heterocyclic compound and psychopharmaceutical composition containing same | SUNTORY LTD (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5158947-A | CONDENSED HETEROCYCLIC COMPOUNDS AND PSYCHOPHARMACEUTICAL COMPOSITION CONTAINING SAME | SUNTORY LIMITED (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0463810-A1 | Heterocyclic compound and psychopharmaceutical composition containing same | SUNTORY LIMITED (JP) | 1992-01-02 | — | — | EP | disclosed |