Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025600 | 0.80 | HTR3E (0.39) | MAPTTP53EGFRKDR | |
| SCHEMBL9219001 | 0.80 | CHKA (0.35) | CYP2C19MAPTTP53L3MBTL1CYP1A2 | |
| SCHEMBL9026363 | 0.78 | SIGMAR1 (0.33) | RAB9ANPC1SMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL9025461 | 0.78 | TP53 (0.35) | RAB9ANPC1CYP3A4MEN1KMT2A | |
| SCHEMBL9026655 | 0.76 | GLA (0.36) | SMN1; SMN2MEN1KMT2AMAPTTP53 | |
| SCHEMBL9992924 | 0.72 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2CYP3A4CYP2C19GPBAR1 | |
| SCHEMBL9025730 | 0.70 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1 | |
| SCHEMBL9025423 | 0.69 | HSD17B10 (0.34) | CYP3A4CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL9025560 | 0.67 | METAP2 (0.40) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9026013 | 0.66 | NPC1 (0.36) | RAB9ANPC1SMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |